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Another study found that in serum, both currently and remitted MDD patients exhibited reduced KYNA to QA ratios compared with healthy controls [38]

Chronic high blood sugar levels initiate a cascade of metabolic abnormalities, which ultimately induce oxidative stress and inflammation, exacerbating nerve injury through excessive production of reactive oxygen species (ROS) and promoting neuronal apoptosis

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It highlights their complementary roles in growth hormone release, focusing on muscle recovery, fat metabolism, sleep quality and anti-aging